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AP Investigative labs: An inquiry-base Approach Lab 3: Comparing DNA Sequences to Understand Evolutionary Relationships with BLAST (Basic Local Alignment Search Tool)

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AP Investigative labs: An inquiry-base Approach Lab 3: Comparing DNA Sequences to Understand Evolutionary Relationships with BLAST (Basic Local Alignment Search Tool)

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In this lab, students use BLAST (Basic Local Alignment Search Tool) to compare several genes, and then use the information to construct a cladogram (also called a phylogenetic tree) to depict the evolutionary relatedness of species.

Subject:: Life Science
Material Type:: Activity/Lab; Assessment; Data Set; Student Guide; Teaching/Learning Strategy
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:: The College Board The College Board (The College Board;)
Date Added:: 10/23/2012

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Antibiotic Attack (Kinetic City)

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This game is a part of the Tau Pack of the Kinetic City site (see description below). In this simulation, the patient's bodies are filled with bacteria. The object is to cure as many patients as possible. Learning concepts enforced here are that antibiotics are specific for the type of bacteria they treat, their strength, and that the bacteria may also become resistant to the bacteria by mutations.KINETIC CITY DESCRIPTION: "Kinetic City" (www.kineticcity.com) is a fun, Web-based after-school science club for kids, ages 8 through 11. It combines exciting online animations and activities with boxes of hands-on science experiments. Children earn "Kinetic City" power points and collect stickers as they complete missions and learn standards-based science content. Here's how it works: The "Kinetic City" super crew (Keisha, Curtis, Megan and Max) needs the help of Earth kids to save their planet Vearth, from the science-distorting computer virus Deep Delete. Each of Deep Delete's 60 hideous strains attacks a different area of science with disastrous consequences. After each attack, teams of Earth kids fight back by viewing a short online animation describing the situation on Vearth; performing a series of activities to re-learn the lost science and going on a mission to Vearth during which they answer science questions and gobble up Deep Delete viruses. Their scores appear on their own Kinetic City Club Web page. "Kinetic City" is produced by the American Association for the Advancement of Science (AAAS), with a grant from the National Science Foundation. AAAS writes the "Project 2061 Benchmarks for Science Literacy," which forms the basis of most state science standards.

Subject:: Engineering; Technology; Education; Life Science
Material Type:: Activity/Lab; Game; Simulation
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Science and Math Informal Learning Educators (SMILE)
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; SMILE Pathway: Science and Math Activities in One Search
Author:: American Association for the Advancement of Science; American Association for the Advancement of Science (;); National Science Foundation
Date Added:: 01/01/2005

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Becoming Human

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Students will experience an interactive documentary that tells the story of our origins and is divided into five sections: Prologue, Evidence, Anatomy, Lineages, and Culture. Students can click on Becoming Human, the Documentary on the left side of the main page. Then they can click on Begin the Program to view the Prologue. In the next four sections, students can click on play the documentary to review each section. The Evidence section reviews how scientists locate, analyze, and interpret fossil evidence. The Anatomy section explores the changing physiology of our ancestors and reviews the unique physical traits that define us as human. The Lineages section takes the user through the evolutionary journeys of our ancestors and reviews how humans are the only surviving branch of a diverse family tree. The last section, Culture, reviews how an advanced culture helps humans understand ourselves, each other, and our place in the natural world.

Subject:: Education; Life Science
Material Type:: Diagram/Illustration; Interactive; Simulation
Provider:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Provider Set:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Author:: Institute of Human Origins (Institute of Human Origins;)
Date Added:: 01/01/2008

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Biochemistry Online: An Approach Based on Chemical Logic

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This site is frequently updated to include newly published findings from Science, Nature, JBC, etc.

Subject:: Computing and Information; Education; Life Science; Mathematics; Chemistry
Material Type:: Data Set; Diagram/Illustration; Full Course; Lecture Notes; Lesson Plan; Simulation; Student Guide
Provider:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; iLumina; Internet Scout Project
Provider Set:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; iLumina Digital Library; Internet Scout Project
Author:: Dr Henry Jakubowski; Henry Jakubowski (College St. Benedict/St. John's University;)
Date Added:: 10/11/2006

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The Biology Project

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Welcome to The Biology Project, an interactive online resource for learning biology developed at The University of Arizona. The Biology Project is fun, richly illustrated, and tested on 1000s of students. It has been designed for biology students at the college level, but is useful for high school students, medical students, physicians, science writers, and all types of interested people. Teachers can assign problems sets for reviews before exams, or may want to assign an activity before students cover that topic in their laboratory. Computers are an excellent means of encouraging cooperative learning, so teachers might even have their students work in small groups. Link to specific Biology Project activities from your course home page, or bookmark The Biology Project on your computer. Students will find that the information covered in The Biology Project is probably just what they've been studying in their introductory biology course, and advanced students will find these materials to be a useful review. All students will benefit from the real-life applications of biology and the inclusion of up-to-date research findings.

Subject:: Education; Life Science; Chemistry; Physics
Material Type:: Activity/Lab; Assessment; Diagram/Illustration; Simulation
Provider:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Provider Set:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Author:: Bill Grimes (University of Arizona;); Cheryl Ryan (University of Arizona;); Douglas Starkey (University of Arizona;); Grimes, Bill.; Joanna K. Norman (University of Arizona;); Ken Williams (University of Arizona;); Michael Wagenheim (University of Arizona;); Rick Hallick (University of Arizona;); Thomas O. Baldwin (University of Arizona;)
Date Added:: 01/01/2000

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Butterflies and moths of North America

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A database detailing the distribution records for Lepidoptera of North America searchable by taxonomic group, region (down to county level) species. Species details include identification, life history, caterpillar hosts, habitat, range and conservation status and more. Although a "work in progress" the site is extensive and has a useful links page for Lepidoptera distribution data around the world. Also included is a good glossary page A valuable resource for Lepidoptera enthusiasts and academics alike.

Subject:: Education; Life Science; Ecology; Forestry and Agriculture; Geoscience
Material Type:: Data Set; Diagram/Illustration
Provider:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Provider Set:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Author:: Opler, Paul A.; Pavulaan, Harry; Stanford, Ray E. (Ray Edmund)
Date Added:: 10/21/2014

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The ChemWiki

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The ChemWiki project is a new approach toward chemistry education where an Open Access textbook environment is constantly being written and re-written partly by students and partly by faculty members resulting in a free Chemistry textbook to supplement or supplant conventional paper-based books. Anyone can view, although a freely available account is required to edit the site modules. The UCD ChemWiki was created and is currently directed by Prof. Delmar Larsen in the Chemistry department at UC Davis.

Subject:: Life Science; Chemistry; Physics
Material Type:: Textbook
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; ComPADRE Digital Library; iLumina
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; ComPADRE: Resources for Physics and Astronomy Education; iLumina Digital Library
Author:: Delmar Larsen (University of California, Davis;Chemistry); Dr. Delmar Larsen
Date Added:: 03/28/2010

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Early movements in science

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Early science was a mix of science, art, and philosophy.

Subject:: Ecology; Forestry and Agriculture; Geoscience
Material Type:: Diagram/Illustration
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Purdue University; Video and Image Data Access (VIDA) Collection
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:: Olivia Worland (Purdue University;Biological Sciences)
Date Added:: 07/07/2008

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Not an Old Person's Disease

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The overall goal of this case study is to introduce students to the genetic basis of cancer development. Students are introduced to a fictional 20-year-old female who sunburns easily and has several other melanoma risk factors. One day, she discovers that a mole on her leg has started to itch. The case study follows her actions as she gets the mole checked out by her doctor and learns more about cancer in the process. Teaching notes written by the authors provide answers to questions and exercises as well as suggestions for use.

Subject:: Life Science
Material Type:: Activity/Lab
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:: Anne Galbraith (University of Wisconsiní˘óîLa Crosse;Department of Biology); Jennifer Miskowski (University of Wisconsiní˘óîLa Crosse;Department of Biology)
Date Added:: 09/23/2002

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Radcliffeí‰ŒÍs IPM World Textbook

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This is the best online textbook teaching IPM for various audiences. The chapters were contributed by internationally recognized experts. The goal for the online textbook is to "eventually have hundreds of chapters relating to integrated pest management in the broad sense (not just insect pest management)."

Subject:: Education; Life Science; Ecology; Forestry and Agriculture; Geoscience
Material Type:: Reading; Textbook
Provider:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Provider Set:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Author:: Hutchison, William D.; Radcliffe, Edward B.
Date Added:: 10/21/2014

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The Science and Ethics of Stem Cell Research

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The Science and Ethics of Stem Cell Research

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This unit, which was designed by teachers in conjunction with scientists, ethicists, and curriculum developers, explores the scientific and ethical issues involved in stem cell research. The unit begins with an exploration of planaria as a model organism for stem cell research. Next, students identify stages in the development of human embryos and compare the types and potency of stem cells. Students learn about a variety of techniques used for obtaining stem cells and the scientific and ethical implications of those techniques. While exploring the ethics of stem cell research, students will develop an awareness of the many shades of gray that exist among positions of stakeholders in the debate. Students will be provided an opportunity to become familiar with policies and regulations for stem cell research that are currently in place in the United States, the issues regarding private and public funding, and the implications for treatment of disease and advancement of scientific knowledge. The unit culminates with students developing a position on embryonic stem cell research through the use of a Decision-Making Framework. Two culminating assessments are offered: In the individual assessment, students write a letter to the President or the Presidents Bioethics Committee describing their position and recommendations; In the group assessment, students develop a proposal for NIH funding to research treatment for a chosen disease using either embryonic or 'adult' stem cells.

Subject:: Education; Life Science
Material Type:: Activity/Lab; Assessment; Diagram/Illustration; Lecture Notes; Lesson Plan; Teaching/Learning Strategy
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:: Jeanne Ting Chowning (Northwest Association for Biomedical Research;); Joan Griswold (Northwest Association for Biomedical Research;)
Date Added:: 05/05/2008

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Science and Technology

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This resource contain various stories both in previous years and to date on Science and technology.

Subject:: Technology; Education; Life Science; Ecology; Forestry and Agriculture; Chemistry; Geoscience; Physics; Space Science
Material Type:: Diagram/Illustration
Provider:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; NSDL Staff
Provider Set:: BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; General Science and STEM Gateways and Resources
Author:: NewsHour with Jim Lehrer; Science Reports (;)
Date Added:: 10/21/2014

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Understanding Disorders at the Cellular Level

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Understanding Disorders at the Cellular Level

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Doctor Daniel Pine discusses the different approaches to understanding disorders and explains that we have a long way to go to understand them on the cellular level.

Subject:: Education; Life Science; Mathematics
Material Type:: Lecture
Provider:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Provider Set:: AMSER: Applied Math and Science Education Repository; BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences; Internet Scout Project
Author:: Caren Gough TITLE; Danielle Sixsmith NOTE;ENCODING=QUOTED-PRINTABLE; David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE); John Connolly (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE); Laura Maitland (Mepham High School TITLE); Mary Colvard TITLE
Date Added:: 12/26/2009

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BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences

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